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Can dogs eat imodium (loperamide)?

Dogs can eat imodium (loperamide), but only in moderation.

Loperamide (Imodium) is occasionally used for dogs under vet guidance, but herding breeds (collies and relatives) with the MDR1 gene can react badly. Always ask your vet first.

🐶 Dogs 🐱 Cats
Verdict
Feed only in moderation
Safe amount
Vet guidance only; risky for collie-type breeds
Species
🐶 Dogs

Why this verdict for dogs

Loperamide (Imodium) is occasionally used for dogs under vet guidance, but herding breeds (collies and relatives) with the MDR1 gene can react badly. Always ask your vet first.

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Frequently asked questions

Can dogs eat imodium (loperamide)?

In moderation. Loperamide (Imodium) is occasionally used for dogs under vet guidance, but herding breeds (collies and relatives) with the MDR1 gene can react badly. Always ask your vet first.

How much imodium (loperamide) can dogs have?

Recommended: Vet guidance only; risky for collie-type breeds. When in doubt, ask your vet.

Is imodium (loperamide) safe for cats too?

Verdicts can differ between species. See the cat answer for imodium (loperamide) →

More medications for dogs

💊 Acetaminophen (Tylenol)💊 Ibuprofen (Advil)💊 Aspirin💊 Melatonin💊 Naproxen (Aleve)💊 Benadryl (diphenhydramine)

By the CanMyPet Editorial Team · Reviewed against ASPCA Animal Poison Control, the American Kennel Club (AKC) and Pet Poison Helpline · Last updated June 2026.

Sources

CanMyPet provides general information reviewed against trusted sources (ASPCA, AKC, Pet Poison Helpline). It is not a substitute for professional veterinary advice. When in doubt, always contact your veterinarian.